The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

MicroRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression through binding to messenger RNAs (mRNA) thereby promoting mRNA degradation or altered translation. A single-nucleotide polymorphism (SNP) located within a miRNA-binding site could thus alter mRNA translation and i...

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Bibliografiske detaljer
Main Authors:	Teo, M, Landi, D, Taylor, C, Elliott, F, Vaslin, L, Cox, D, Hall, J, Landi, S, Bishop, D, Kiltie, A
Format:	Journal article
Sprog:	English
Udgivet:	2012

Lignende værker

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af: Bishop D Timothy, et al.
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af: Sak, S, et al.
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Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.
af: Stern, M, et al.
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Molecular epidemiology of DNA repair genes in bladder cancer.
af: Kiltie, A
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af: Qiao, B, et al.
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af: Choudhury, A, et al.
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af: Choudhury, A, et al.
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af: Teo, M, et al.
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af: Teo, T, et al.
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In vitro functional effects of XPC gene rare variants from bladder cancer patients.
af: Qiao, B, et al.
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Analysis of variants in DNA damage signalling genes in bladder cancer
af: Bishop D Timothy, et al.
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Common predisposition alleles for moderately common cancers: bladder cancer.
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RAD51: A DNA repair target for increasing the therapeutic potential in bladder cancer
af: Choudhury, A, et al.
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APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer.
af: Sak, S, et al.
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Single Nucleotide Polymorphisms in MicroRNA Binding Sites: Implications in Colorectal Cancer
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The polyAT, intronic IVS11-6 and Lys939Gln XPC polymorphisms are not associated with transitional cell carcinoma of the bladder.
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Phase II study of conformal hypofractionated radiotherapy with concurrent gemcitabine in muscle-invasive bladder cancer.
af: Choudhury, A, et al.
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Gemcitabine as a Chemoradiosensitiser in Bladder Cancer
af: Kerr, M, et al.
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Predictive Biomarkers for Gemcitabine as a Chemoradiosensitizer in Bladder Cancer
af: Kerr, M, et al.
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af: Yue Zhao, et al.
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A multicentre NCRI phase II study of hypofractionated conformal radiotherapy with concurrent gemcitabine in muscle-invasive bladder cancer
af: Choudhury, A, et al.
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Utility of bladder-sparing therapy vs radical cystectomy for muscle-invasive bladder cancer
af: Efstathiou, J, et al.
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Feasibility of magnetic resonance guided radiotherapy for the treatment of bladder cancer
af: A. Hunt, et al.
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Imatinib radiosensitizes bladder cancer by targeting homologous recombination.
af: Qiao, B, et al.
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DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining.
af: Bentley, J, et al.
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af: Zhiwei Chen, et al.
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af: Sofia Khan, et al.
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Comparison of treatment outcome for radical surgery versus radical radiotherapy for invasive bladder cancer treated in a UK specialist treatment centre
af: Kotwal, S, et al.
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Similar treatment outcomes for radical cystectomy and radical radiotherapy in invasive bladder cancer treated at a United Kingdom specialist treatment center.
af: Kotwal, S, et al.
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