The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

MicroRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression through binding to messenger RNAs (mRNA) thereby promoting mRNA degradation or altered translation. A single-nucleotide polymorphism (SNP) located within a miRNA-binding site could thus alter mRNA translation and i...

書目詳細資料
Main Authors:	Teo, M, Landi, D, Taylor, C, Elliott, F, Vaslin, L, Cox, D, Hall, J, Landi, S, Bishop, D, Kiltie, A
格式:	Journal article
語言:	English
出版:	2012

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