A new inhibitor of apoptosis from vaccinia virus and eukaryotes.

A new apoptosis inhibitor is described from vaccinia virus, camelpox virus, and eukaryotic cells. The inhibitor is a hydrophobic, multiple transmembrane protein that is resident in the Golgi and is named GAAP (Golgi anti-apoptotic protein). Stable expression of both viral GAAP (v-GAAP) and human GAA...

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Détails bibliographiques
Auteurs principaux: Gubser, C, Bergamaschi, D, Hollinshead, M, Lu, X, van Kuppeveld, F, Smith, G
Format: Journal article
Langue:English
Publié: Public Library of Science 2007