Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000.
OBJECTIVE: To describe national patterns of use of hormone replacement therapy (HRT) in 1996-2000. DESIGN: Population-based study of women aged 50-64. SETTING: England and Scotland. POPULATION: A total of 1,091,250 women were recruited between May 1996 and December 2000. METHODS: Women invited for s...
প্রধান লেখক: | |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2002
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author | Million Women Study Collaborators |
author_facet | Million Women Study Collaborators |
author_sort | Million Women Study Collaborators |
collection | OXFORD |
description | OBJECTIVE: To describe national patterns of use of hormone replacement therapy (HRT) in 1996-2000. DESIGN: Population-based study of women aged 50-64. SETTING: England and Scotland. POPULATION: A total of 1,091,250 women were recruited between May 1996 and December 2000. METHODS: Women invited for screening at 66 NHS breast screening units were sent a questionnaire to complete before they were screened; 71% of women screened participated. Prevalence of use of HRT. RESULTS: Overall, 33% of women reported that they were currently using HRT, the average duration of use being 5.8 years; 50% were ever-users. Current use of HRT was about twice as common at age 50-54 than 60-64, but varied little by time or region, the prevalences being 33%-34% in each year from 1996 to 2000; 30% in Scotland and 35% in southeast England. The prevalence of current use of HRT varied substantially depending on the woman's history of gynaecological surgery and past health, and was as follows in women with a history of: bilateral oophorectomy (66%); hysterectomy without bilateral oophorectomy (48%); neither hysterectomy nor bilateral oophorectomy (27%); breast cancer (6%); other cancer (25%); stroke (24%); venous thromboembolism (24%); diabetes (25%); heart disease (31%); or hypertension (31%). There was considerably less variation in the prevalence of use of HRT according to deprivation index, education, parity, body mass index, exercise, smoking or alcohol consumption. CONCLUSIONS: HRT is currently used by around one-third of women aged 50-64 in Britain and appears to be influenced considerably more strongly by a woman's medical and surgical history than by socio-economic or lifestyle factors. |
first_indexed | 2024-03-06T22:10:50Z |
format | Journal article |
id | oxford-uuid:51c0dffe-f714-4d2f-aa13-3c9ef1cfa4fe |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T22:10:50Z |
publishDate | 2002 |
record_format | dspace |
spelling | oxford-uuid:51c0dffe-f714-4d2f-aa13-3c9ef1cfa4fe2022-03-26T16:21:25ZPatterns of use of hormone replacement therapy in one million women in Britain, 1996-2000.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:51c0dffe-f714-4d2f-aa13-3c9ef1cfa4feEnglishSymplectic Elements at Oxford2002Million Women Study CollaboratorsOBJECTIVE: To describe national patterns of use of hormone replacement therapy (HRT) in 1996-2000. DESIGN: Population-based study of women aged 50-64. SETTING: England and Scotland. POPULATION: A total of 1,091,250 women were recruited between May 1996 and December 2000. METHODS: Women invited for screening at 66 NHS breast screening units were sent a questionnaire to complete before they were screened; 71% of women screened participated. Prevalence of use of HRT. RESULTS: Overall, 33% of women reported that they were currently using HRT, the average duration of use being 5.8 years; 50% were ever-users. Current use of HRT was about twice as common at age 50-54 than 60-64, but varied little by time or region, the prevalences being 33%-34% in each year from 1996 to 2000; 30% in Scotland and 35% in southeast England. The prevalence of current use of HRT varied substantially depending on the woman's history of gynaecological surgery and past health, and was as follows in women with a history of: bilateral oophorectomy (66%); hysterectomy without bilateral oophorectomy (48%); neither hysterectomy nor bilateral oophorectomy (27%); breast cancer (6%); other cancer (25%); stroke (24%); venous thromboembolism (24%); diabetes (25%); heart disease (31%); or hypertension (31%). There was considerably less variation in the prevalence of use of HRT according to deprivation index, education, parity, body mass index, exercise, smoking or alcohol consumption. CONCLUSIONS: HRT is currently used by around one-third of women aged 50-64 in Britain and appears to be influenced considerably more strongly by a woman's medical and surgical history than by socio-economic or lifestyle factors. |
spellingShingle | Million Women Study Collaborators Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title | Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title_full | Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title_fullStr | Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title_full_unstemmed | Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title_short | Patterns of use of hormone replacement therapy in one million women in Britain, 1996-2000. |
title_sort | patterns of use of hormone replacement therapy in one million women in britain 1996 2000 |
work_keys_str_mv | AT millionwomenstudycollaborators patternsofuseofhormonereplacementtherapyinonemillionwomeninbritain19962000 |