A role for solvents in the toxicity of agricultural organophosphorus pesticides.

A role for solvents in the toxicity of agricultural organophosphorus pesticides.

Organophosphorus (OP) insecticide self-poisoning is responsible for about one-quarter of global suicides. Treatment focuses on the fact that OP compounds inhibit acetylcholinesterase (AChE); however, AChE-reactivating drugs do not benefit poisoned humans. We therefore studied the role of solvent cof...

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Bibliographic Details
Main Authors: Eddleston, M, Street, J, Self, I, Thompson, A, King, T, Williams, N, Naredo, G, Dissanayake, K, Yu, L, Worek, F, John, H, Smith, S, Thiermann, H, Harris, J, Eddie Clutton, R
Format: Journal article
Language:English
Published: 2012

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