Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network
Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied here a Bayesian selectivity model to predict hundred...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
Public Library of Science
2011
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