Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.

This study aimed to find out whether preoperative diffusion tensor imaging (DTI) and probabilistic tractography could help with surgical planning for deep brain stimulation in the periaqueductal/periventricular grey area (PAG/PVG) in a patient with lower leg stump pain. A preoperative DTI was obtain...

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Main Authors: Owen, S, Heath, J, Kringelbach, M, Stein, J, Aziz, T
Format: Journal article
Language:English
Published: 2007
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author Owen, S
Heath, J
Kringelbach, M
Stein, J
Aziz, T
author_facet Owen, S
Heath, J
Kringelbach, M
Stein, J
Aziz, T
author_sort Owen, S
collection OXFORD
description This study aimed to find out whether preoperative diffusion tensor imaging (DTI) and probabilistic tractography could help with surgical planning for deep brain stimulation in the periaqueductal/periventricular grey area (PAG/PVG) in a patient with lower leg stump pain. A preoperative DTI was obtained from the patient, who then received DBS surgery in the PAG/PVG area with good pain relief. The postoperative MRI scan showing electrode placement was used to calculate four seed areas to represent the contacts on the Medtronic 3387 electrode. Probabilistic tractography was then performed from the pre-operative DTI image. Tracts were seen to connect to many areas within the pain network from the four different contacts. These initial findings suggest that preoperative DTI scanning and probabilistic tractography may be able to assist surgical planning in the future.
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spelling oxford-uuid:51f8211d-e4bb-4a6c-9894-3d074cf76ea62022-03-26T16:22:48ZPreoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:51f8211d-e4bb-4a6c-9894-3d074cf76ea6EnglishSymplectic Elements at Oxford2007Owen, SHeath, JKringelbach, MStein, JAziz, TThis study aimed to find out whether preoperative diffusion tensor imaging (DTI) and probabilistic tractography could help with surgical planning for deep brain stimulation in the periaqueductal/periventricular grey area (PAG/PVG) in a patient with lower leg stump pain. A preoperative DTI was obtained from the patient, who then received DBS surgery in the PAG/PVG area with good pain relief. The postoperative MRI scan showing electrode placement was used to calculate four seed areas to represent the contacts on the Medtronic 3387 electrode. Probabilistic tractography was then performed from the pre-operative DTI image. Tracts were seen to connect to many areas within the pain network from the four different contacts. These initial findings suggest that preoperative DTI scanning and probabilistic tractography may be able to assist surgical planning in the future.
spellingShingle Owen, S
Heath, J
Kringelbach, M
Stein, J
Aziz, T
Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title_full Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title_fullStr Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title_full_unstemmed Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title_short Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain.
title_sort preoperative dti and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain
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