A mutation in X-linked inhibitor of apoptosis (G466X) leads to memory inflation of Epstein-Barr virus-specific T cells.

A mutation in X-linked inhibitor of apoptosis (G466X) leads to memory inflation of Epstein-Barr virus-specific T cells.

Mutations in the X-linked inhibitor of apoptosis (XIAP) gene have been associated with XLP-like disease, including recurrent Epstein-Barr virus (EBV)-related haemophagocytic lymphohystiocytosis (HLH), but the immunopathogenic bases of EBV-related disease in XIAP deficiency is unknown. We present the...

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Bibliographic Details
Main Authors: Lopez-Granados, E, Stacey, M, Kienzler, A, Sierro, S, Willberg, C, Fox, C, Rigaud, S, Long, H, Hislop, A, Rickinson, AB, Patel, S, Latour, S, Klenerman, P, Chapel, H
Format: Journal article
Language:English
Published: Blackwell Publishing Ltd 2014

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