Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells.

Interferon (IFN)-gamma was originally characterized as a pro-inflammatory cytokine with T helper type 1-inducing activity, but subsequent work has demonstrated that mice deficient in IFN-gamma or IFN-gamma receptor show exacerbated inflammatory responses and accelerated allograft rejection, suggesti...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Feng, G, Gao, W, Strom, T, Oukka, M, Francis, R, Wood, K, Bushell, A
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2008