Role of RAD51C and XRCC3 in genetic recombination and DNA repair.

In germ line cells, recombination is required for gene reassortment and proper chromosome segregation at meiosis, whereas in somatic cells it provides an important mechanism for the repair of DNA double-strand breaks. Five proteins (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) that share homology with...

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Autors principals: Liu, Y, Tarsounas, M, O'regan, P, West, S
Format: Journal article
Idioma:English
Publicat: 2007