Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry
Euglena gracilis is a eukaryotic microalgae that has been the subject of scientific study for hundreds of years. It has a complex evolutionary history, with traces of at least four endosymbiotic genomes and extensive horizontal gene transfer. Given the importance of Euglena in terms of evolutionary...
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| Format: | Journal article |
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Elsevier
2015
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| _version_ | 1797068609451720704 |
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| author | O’Neill, E Trick, M Henrissat, B Field, R |
| author_facet | O’Neill, E Trick, M Henrissat, B Field, R |
| author_sort | O’Neill, E |
| collection | OXFORD |
| description | Euglena gracilis is a eukaryotic microalgae that has been the subject of scientific study for hundreds of years. It has a complex evolutionary history, with traces of at least four endosymbiotic genomes and extensive horizontal gene transfer. Given the importance of Euglena in terms of evolutionary cell biology and its unique taxonomic position, we initiated a de novo transcriptome sequencing project in order to understand this intriguing organism. By analysing the proteins encoded in this transcriptome, we can identify an extremely complex metabolic capacity, rivalling that of multicellular organisms. Many genes have been acquired from what are now very distantly related species. Herein we consider the biology of Euglena in different time frames, from evolution through control of cell biology to metabolic processes associated with carbohydrate and natural products biochemistry. |
| first_indexed | 2024-03-06T22:12:37Z |
| format | Journal article |
| id | oxford-uuid:525387ea-bd60-43f4-b86a-a12f8a9cbdde |
| institution | University of Oxford |
| last_indexed | 2024-03-06T22:12:37Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:525387ea-bd60-43f4-b86a-a12f8a9cbdde2022-03-26T16:24:55ZEuglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:525387ea-bd60-43f4-b86a-a12f8a9cbddeSymplectic Elements at OxfordElsevier2015O’Neill, ETrick, MHenrissat, BField, REuglena gracilis is a eukaryotic microalgae that has been the subject of scientific study for hundreds of years. It has a complex evolutionary history, with traces of at least four endosymbiotic genomes and extensive horizontal gene transfer. Given the importance of Euglena in terms of evolutionary cell biology and its unique taxonomic position, we initiated a de novo transcriptome sequencing project in order to understand this intriguing organism. By analysing the proteins encoded in this transcriptome, we can identify an extremely complex metabolic capacity, rivalling that of multicellular organisms. Many genes have been acquired from what are now very distantly related species. Herein we consider the biology of Euglena in different time frames, from evolution through control of cell biology to metabolic processes associated with carbohydrate and natural products biochemistry. |
| spellingShingle | O’Neill, E Trick, M Henrissat, B Field, R Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title | Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title_full | Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title_fullStr | Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title_full_unstemmed | Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title_short | Euglena in time: evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry |
| title_sort | euglena in time evolution control of central metabolic processes and multi domain proteins in carbohydrate and natural product biochemistry |
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