Determining the influence of structure on hybridization using oligonucleotide arrays.
We have studied the effects of structure on nucleic acid heteroduplex formation by analyzing hybridization of tRNAphe to a complete set of complementary oligonucleotides, ranging from single nucleotides to dodecanucleotides. The analysis points to features in tRNA that determine heteroduplex yield....
Hlavní autoři: | , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1999
|