Determining the influence of structure on hybridization using oligonucleotide arrays.
We have studied the effects of structure on nucleic acid heteroduplex formation by analyzing hybridization of tRNAphe to a complete set of complementary oligonucleotides, ranging from single nucleotides to dodecanucleotides. The analysis points to features in tRNA that determine heteroduplex yield....
| Main Authors: | , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
1999
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