Heritability of variation in glycaemic response to metformin: A genome-wide complex trait analysis

Heritability of variation in glycaemic response to metformin: A genome-wide complex trait analysis

Show other versions (1)

Background: Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish t...

Full description

Bibliographic Details
Main Authors:	Zhou, K, Donnelly, L, Yang, J, Li, M, Deshmukh, H, Van Zuydam, N, Ahlqvist, E, Spencer, C, Groop, L, Morris, A, Colhoun, H, Sham, P, McCarthy, M, Palmer, C, Pearson, E
Format:	Journal article
Published:	2014

Similar Items

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis.
by: Zhou, K, et al.
Published: (2014)

Mechanisms of NKG2D ligand regulation
by: McCarthy, M, et al.
Published: (2013)

Making the right associations.
by: McCarthy, M, et al.
Published: (2005)

Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study.
by: Donnelly, L, et al.
Published: (2011)

Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with Type 2 diabetes: A Go-DARTS study
by: Donnelly, L, et al.
Published: (2011)

Pharmacogenetics in Type 2 diabetes: variation in TCF7L2 influences response to sulphonylureas
by: Pearson, E, et al.
Published: (2007)

ARE WE MEETING STUDENT EXPECTATIONS: STUDENT PERCEPTIONS OF ADVISING IN THE NEW MILLENIUM
by: Mary McCarthy, et al.
Published: (2011-01-01)

The Genetic Landscape of Renal Complications in Type 1 Diabetes
by: Sandholm, N, et al.
Published: (2016)

Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study.
by: Zhou, K, et al.
Published: (2009)

A time of transition: changes in Irish food behaviour and potential implications due to the COVID-19 pandemic
by: M. Henchion, et al.
Published: (2021-05-01)

Autocad express /
by: 465379 McCarthy, Tim, et al.
Published: (1992)

Dorothy Hodgkin Lecture 2010. From hype to hope? A journey through the genetics of Type 2 diabetes.
by: McCarthy, M
Published: (2011)

Growing evidence for diabetes susceptibility genes from genome scan data.
by: McCarthy, M
Published: (2003)

GENOMIC MEDICINE Genomics, Type 2 Diabetes, and Obesity
by: McCarthy, M
Published: (2010)

Genetics of T2DM in 2016: Biological and translational insights from T2DM genetics
by: McCarthy, M
Published: (2017)

Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification.
by: McCarthy, M
Published: (2004)

Erratum to: Painting a new picture of personalised medicine for diabetes
by: McCarthy, M
Published: (2017)

Exploring the unknown: assumptions about allelic architecture and strategies for susceptibility variant discovery.
by: McCarthy, M
Published: (2009)

Painting a new picture of personalised medicine for diabetes
by: McCarthy, M
Published: (2017)

What will genome-wide association studies mean to the clinical endocrinologist?
by: McCarthy, M
Published: (2009)

Genomics, type 2 diabetes, and obesity.
by: McCarthy, M
Published: (2010)

The importance of global studies of the genetics of type 2 diabetes.
by: McCarthy, M
Published: (2011)

Casting a wider net for diabetes susceptibility genes.
by: McCarthy, M
Published: (2008)

Essays in empirical macroeconomics and finance
by: McCarthy, M
Published: (2023)

Abolishing franking credit refunds: evidence from an event study
by: McCarthy, M
Published: (2020)

Pharmacological interventions for ADHD: how do adolescent and adult patient beliefs and attitudes impact treatment adherence?
by: McCarthy S
Published: (2014-09-01)

Teaching around the 4MAT cycle : designing instruction for diverse learners with diverse learning styles /
by: 465039 McCarthy, Bernice, et al.
Published: (2006)

Supraglacial debris thickness variability: impact on ablation and relation to terrain properties
by: L. I. Nicholson, et al.
Published: (2018-11-01)

Ovarian morphology is a marker of heritable biochemical traits in sisters with polycystic ovaries.
by: Franks, S, et al.
Published: (2008)

Recent Developments in the Genetic and Genomic Basis of Type 2 Diabetes
by: Richards, H, et al.
Published: (2013)

Getting it right this time : how to create a loving and lasting marriage /
by: McCarthy, Barry W., 1943-, et al.
Published: (2006)

Mechanisms of disease: genetic insights into the etiology of type 2 diabetes and obesity.
by: Lindgren, C, et al.
Published: (2008)

Genetic studies of diabetes following the advent of the genome-wide association study: where do we go from here?
by: Frayling, T, et al.
Published: (2007)

Designation : the use of information-based strategies in planning and preservation
by: McCarthy, Danielle M
Published: (2006)

Franz Grillparzer's dramatic heroines and women's emancipation in nineteenth-century Austria
by: McCarthy-Rechowicz, M
Published: (2016)

Identifying susceptibility variants for type 2 diabetes.
by: Zeggini, E, et al.
Published: (2007)

Human genetics of obesity and type 2 diabetes mellitus: past, present, and future
by: Ingelsson, E, et al.
Published: (2018)

TCF7L2: the biggest story in diabetes genetics since HLA?
by: Zeggini, E, et al.
Published: (2007)

Genetics of type 2 diabetes.
by: McCarthy, M, et al.
Published: (2006)

Genome-wide association studies in type 2 diabetes.
by: McCarthy, M, et al.
Published: (2009)