Defective B cell responses in the absence of SH2D1A.
More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-Barr virus. One-third of these patients, however, develop dysgammaglobulenemia without an episode of severe...
Main Authors: | Morra, M, Barrington, R, Abadia-Molina, A, Okamoto, S, Julien, A, Gullo, C, Kalsy, A, Edwards, M, Chen, G, Spolski, R, Leonard, W, Huber, B, Borrow, P, Biron, C, Satoskar, A, Carroll, M, Terhorst, C |
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Format: | Journal article |
Language: | English |
Published: |
2005
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