Genetic and epigenetic studies of adiposity and cardiometabolic disease.
Over 300 million adults are obese, but little is known about the impact of obesity on cardiovascular health. We discuss recent genetic and epigenetic studies of adiposity that indicate a causal role for general and central adiposity in cardiometabolic disease, and highlight potential mechanisms incl...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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BioMed Central
2017
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| _version_ | 1797068668747644928 |
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| author | Holmes, M Pulit, S Lindgren, C |
| author_facet | Holmes, M Pulit, S Lindgren, C |
| author_sort | Holmes, M |
| collection | OXFORD |
| description | Over 300 million adults are obese, but little is known about the impact of obesity on cardiovascular health. We discuss recent genetic and epigenetic studies of adiposity that indicate a causal role for general and central adiposity in cardiometabolic disease, and highlight potential mechanisms including insulin resistance and gene expression. |
| first_indexed | 2024-03-06T22:13:29Z |
| format | Journal article |
| id | oxford-uuid:529cf961-6b23-48d0-89c1-75d561d774a3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:13:29Z |
| publishDate | 2017 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:529cf961-6b23-48d0-89c1-75d561d774a32022-03-26T16:26:35ZGenetic and epigenetic studies of adiposity and cardiometabolic disease.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:529cf961-6b23-48d0-89c1-75d561d774a3EnglishSymplectic Elements at OxfordBioMed Central2017Holmes, MPulit, SLindgren, COver 300 million adults are obese, but little is known about the impact of obesity on cardiovascular health. We discuss recent genetic and epigenetic studies of adiposity that indicate a causal role for general and central adiposity in cardiometabolic disease, and highlight potential mechanisms including insulin resistance and gene expression. |
| spellingShingle | Holmes, M Pulit, S Lindgren, C Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title | Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title_full | Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title_fullStr | Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title_full_unstemmed | Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title_short | Genetic and epigenetic studies of adiposity and cardiometabolic disease. |
| title_sort | genetic and epigenetic studies of adiposity and cardiometabolic disease |
| work_keys_str_mv | AT holmesm geneticandepigeneticstudiesofadiposityandcardiometabolicdisease AT pulits geneticandepigeneticstudiesofadiposityandcardiometabolicdisease AT lindgrenc geneticandepigeneticstudiesofadiposityandcardiometabolicdisease |