A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells.
There are few studies that have investigated T cell mediated lysis of adherent cells. We have developed a novel, rapid and sensitive fluorescent dye-swap assay that allows efficient detection of adherent target cell lysis. The assay allows simultaneous use of multiple differentially sensitised targe...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
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2006
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_version_ | 1797068677484380160 |
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author | Black, A Jones, L Ardern-Jones, M Ogg, G |
author_facet | Black, A Jones, L Ardern-Jones, M Ogg, G |
author_sort | Black, A |
collection | OXFORD |
description | There are few studies that have investigated T cell mediated lysis of adherent cells. We have developed a novel, rapid and sensitive fluorescent dye-swap assay that allows efficient detection of adherent target cell lysis. The assay allows simultaneous use of multiple differentially sensitised targets and facilitates concomitant surface or intracellular effector cell phenotypic analysis. |
first_indexed | 2024-03-06T22:13:37Z |
format | Journal article |
id | oxford-uuid:52a82590-25f1-44e9-b679-58d2b2e1db6c |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T22:13:37Z |
publishDate | 2006 |
record_format | dspace |
spelling | oxford-uuid:52a82590-25f1-44e9-b679-58d2b2e1db6c2022-03-26T16:26:47ZA novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:52a82590-25f1-44e9-b679-58d2b2e1db6cEnglishSymplectic Elements at Oxford2006Black, AJones, LArdern-Jones, MOgg, GThere are few studies that have investigated T cell mediated lysis of adherent cells. We have developed a novel, rapid and sensitive fluorescent dye-swap assay that allows efficient detection of adherent target cell lysis. The assay allows simultaneous use of multiple differentially sensitised targets and facilitates concomitant surface or intracellular effector cell phenotypic analysis. |
spellingShingle | Black, A Jones, L Ardern-Jones, M Ogg, G A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title | A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title_full | A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title_fullStr | A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title_full_unstemmed | A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title_short | A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells. |
title_sort | novel fluorescent sensitive assay for detection of differential t cell mediated lysis of multiple adherent target cells |
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