The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Dulloo, I, Muliyil, S, Freeman, M
Format: Journal article
Sprache:English
Veröffentlicht: Royal Society 2019