Coenzyme B induced coordination of coenzyme M via its thiol group to Ni(I) of F430 in active methyl-coenzyme M reductase.
Methyl-coenzyme M reductase (MCR) catalyzes the reaction of methyl-coenzyme M (CH3-S-CoM) with coenzyme B (HS-CoB) to methane and CoM-S-S-CoB. At the active site, it contains the nickel porphinoid F430, which has to be in the Ni(I) oxidation state for the enzyme to be active. How the substrates inte...
Những tác giả chính: | Finazzo, C, Harmer, J, Bauer, C, Jaun, B, Duin, E, Mahlert, F, Goenrich, M, Thauer, R, Van Doorslaer, S, Schweiger, A |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2003
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