Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome.
The Mendelian tumour syndromes hereditary leiomyomatosis and renal cell cancer (HLRCC) and hereditary paragangliomatosis with phaeochromocytomas (HPGL) result from mutations in nuclear genes (FH and SDHB/C/D, respectively) that encode Krebs cycle enzymes. HPGL tumours are highly vascular and there i...
Հիմնական հեղինակներ: | Pollard, P, Wortham, N, Barclay, E, Alam, A, Elia, G, Manek, S, Poulsom, R, Tomlinson, I |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2005
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Նմանատիպ նյութեր
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Aberrant expression of apoptosis proteins and ultrastructural aberrations in uterine leiomyomas from patients with hereditary leiomyomatosis and renal cell carcinoma.
: Wortham, N, և այլն
Հրապարակվել է: (2006) -
Aberrant expression of apoptosis proteins and ultrastructural aberrations in uterine leiomyomas from patients with hereditary leiomyomatosis and renal cell carcinoma
: Wortham, N, և այլն
Հրապարակվել է: (2006) -
Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency.
: Alam, N, և այլն
Հրապարակվել է: (2003) -
Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency
: Alam, N, և այլն
Հրապարակվել է: (2003) -
Hereditary leiomyomatosis and renal cell carcinoma
: Schmidt LS, և այլն
Հրապարակվել է: (2014-06-01)