Identification of a bifunctional lipopolysaccharide sialyltransferase in Haemophilus influenzae: incorporation of disialic acid.

The lipopolysaccharide (LPS) of non-typeable Haemophilus influenzae (NTHi) can be substituted at various positions by N-acetylneuraminic acid (Neu5Ac). LPS sialylation plays an important role in pathogenesis. The only LPS sialyltransferase characterized biochemically to date in H. influenzae is Lic3...

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Príomhchruthaitheoirí: Fox, K, Cox, A, Gilbert, M, Wakarchuk, W, Li, J, Makepeace, K, Richards, J, Moxon, E, Hood, D
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2006