Crystallization and functional analysis of a soluble deglycosylated form of the human costimulatory molecule B7-1.

Crystallization and functional analysis of a soluble deglycosylated form of the human costimulatory molecule B7-1.

The interactions of B7-1 with CD28 and CTLA-4 modulate the course of human immune responses, making B7-1 an important target for developing structure-based therapeutics. B7-1 is, however, one of the most heavily glycosylated proteins found at the leukocyte cell surface, complicating the structural a...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Davis, S, Ikemizu, S, Collins, A, Fennelly, J, Harlos, K, Jones, E, Stuart, D
Natura:	Journal article
Lingua:	English
Pubblicazione:	2001

Documenti analoghi

Structure and dimerization of a soluble form of B7-1.
di: Ikemizu, S, et al.
Pubblicazione: (2000)

Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
di: Jones, E, et al.
Pubblicazione: (1992)

Structural studies on the leukocyte co-stimulatory molecule, B7-1
di: Ikemizu, S, et al.
Pubblicazione: (2001)

The interaction properties of costimulatory molecules revisited.
di: Collins, A, et al.
Pubblicazione: (2002)

An evolutionary and functional analysis of the extended B7 family of costimulatory molecules
di: Iaboni, A, et al.
Pubblicazione: (2002)

LICOS, a primordial costimulatory ligand?
di: Brodie, D, et al.
Pubblicazione: (2000)

Expression of costimulatory molecules in the bovine corpus luteum
di: Pate Joy L, et al.
Pubblicazione: (2007-01-01)

Diagnostic significance of soluble adhesion molecules and costimulatory molecules of immune cells in the patients with ischemic heart disease
di: A. V. Logatkina, et al.
Pubblicazione: (2020-01-01)

Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer
di: Kleeff Jörg, et al.
Pubblicazione: (2009-12-01)

Tumour cells expressing B7.1 costimulatory molecule: Are these better targets for NK cells?
di: GaleaLauri, J, et al.
Pubblicazione: (1996)

Enhancement of the Soluble Form of OX40 and OX40L Costimulatory Molecules but Reduction of the Membrane Form in Type 1 Diabetes (T1D)
di: Jingnan An, et al.
Pubblicazione: (2019-01-01)

Neuroimmune semaphorins as costimulatory molecules and beyond
di: Svetlana P. Chapoval
Pubblicazione: (2018-04-01)

Expression of the Costimulatory Molecule B7-H4 in the Decidua and Placental Tissues in Patients with Placental Abruption
di: Monika Bączkowska, et al.
Pubblicazione: (2022-04-01)

Evaluation of costimulatory molecules in dogs with B cell high grade lymphoma.
di: Michihito Tagawa, et al.
Pubblicazione: (2018-01-01)

Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization.
di: Butters, T, et al.
Pubblicazione: (1999)

Kinetic Changes in B7 Costimulatory Molecules and IRF4 Expression in Human Dendritic Cells during LPS Exposure
di: Henry Velazquez-Soto, et al.
Pubblicazione: (2022-07-01)

Heterologous expression of human costimulatory molecule B7-2 and construction of B7-2 immobilized polyhydroxyalkanoate nanoparticles for use as an immune activation agent
di: Li Ming-Chuan, et al.
Pubblicazione: (2012-07-01)

Costimulatory molecules on immunogenic versus tolerogenic human dendritic cells
di: Mario eHubo, et al.
Pubblicazione: (2013-04-01)

Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
di: Bodian, D, et al.
Pubblicazione: (1994)

The role of costimulatory molecules in glioma biology and immune microenvironment
di: Ji Wang, et al.
Pubblicazione: (2022-11-01)

Bispecific costimulatory molecules for activation of tumor-killing lymphocytes
di: Wels W, et al.
Pubblicazione: (2004-07-01)

Contributions of Costimulatory Molecule CD137 in Endothelial Cells
di: Wei Yuan, et al.
Pubblicazione: (2021-06-01)

Fcμ receptor as a Costimulatory Molecule for T Cells
di: Andreas Meryk, et al.
Pubblicazione: (2019-03-01)

The N-glycan glycoprotein deglycosylation complex (Gpd) from Capnocytophaga canimorsus deglycosylates human IgG.
di: Francesco Renzi, et al.
Pubblicazione: (2011-06-01)

Negative costimulatory molecule B7-H4 mediates protective effect of mesenchymal stem cells on experimental autoimmune encephalomyelitis
di: Xiao-Pei Ji, et al.
Pubblicazione: (2022-12-01)

Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
di: Ikemizu, S, et al.
Pubblicazione: (1999)

DEVELOPMENT OF A SYSTEM OF EXPRESSION CLONING FOR MOLECULES COSTIMULATORY FOR T-CELLS
di: Murray, N, et al.
Pubblicazione: (1994)

Manipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici!!
di: Nargis Khan, et al.
Pubblicazione: (2012-01-01)

Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2.
di: Davis, S, et al.
Pubblicazione: (1993)

Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity
di: Yu Fu, et al.
Pubblicazione: (2020-03-01)

Structure characterization and IgE-binding of soybean 7S globulin after enzymatic deglycosylation
di: Anshu Yang, et al.
Pubblicazione: (2018-01-01)

T Cell Costimulatory Molecules in Anti-Viral Immunity: Potential Role in Immunotherapeutic Vaccines
di: Tania H Watts, et al.
Pubblicazione: (2003-01-01)

Graft-versus-host disease: establishing IL-33 as an important costimulatory molecule
di: James Ferrara, et al.
Pubblicazione: (2022-06-01)

Costimulatory Molecules and Immune Checkpoints Are Differentially Expressed on Different Subsets of Dendritic Cells
di: Claudia Carenza, et al.
Pubblicazione: (2019-06-01)

Evaluation of Costimulatory Molecules in Peripheral Blood Lymphocytes of Canine Patients with Histiocytic Sarcoma.
di: Michihito Tagawa, et al.
Pubblicazione: (2016-01-01)

The Common Costimulatory and Coinhibitory Signaling Molecules in Head and Neck Squamous Cell Carcinoma
di: Peng Liao, et al.
Pubblicazione: (2019-10-01)

Deglycosylation of eukaryotic-expressed flagellin restores adjuvanticity
di: Koemchhoy Khim, et al.
Pubblicazione: (2023-09-01)

Too sweet: cheminformatics for deglycosylation in natural products
di: Jonas Schaub, et al.
Pubblicazione: (2020-11-01)

Liver Involvement in Congenital Disorders of Glycosylation and Deglycosylation
di: Patryk Lipiński, et al.
Pubblicazione: (2021-07-01)

Adenoviral delivery of soluble ovine OX40L or CD70 costimulatory molecules improves adaptive immune responses to a model antigen in sheep
di: José M. Rojas, et al.
Pubblicazione: (2022-09-01)