4D Visualization of replication foci in mammalian cells corresponding to individual replicons
Since the pioneering proposal of the replicon model of DNA replication 50 years ago, the predicted replicons have not been identified and quantified at the cellular level. Here, we combine conventional and super-resolution microscopy of replication sites in live and fixed cells with computational im...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2016
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