4D Visualization of replication foci in mammalian cells corresponding to individual replicons

4D Visualization of replication foci in mammalian cells corresponding to individual replicons

Since the pioneering proposal of the replicon model of DNA replication 50 years ago, the predicted replicons have not been identified and quantified at the cellular level. Here, we combine conventional and super-resolution microscopy of replication sites in live and fixed cells with computational im...

Full description

Bibliographic Details
Main Authors: Chagin, V, Casas-Delucchi, C, Reinhart, MR, Schermelleh, L, Markaki, Y, Maiser, A, Bolius, J, Bensimon, AB, Filies, M, Domaing, P, Rozanov, Y, Leonhardt, H, Cardoso, M
Format: Journal article
Published: Nature Publishing Group 2016

Similar Items

Similar Items