Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome.

Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome.

The Phosphatase And Tensin Homolog Deleted On Chromosome 10 (PTEN) regulates the phosphoinositol-3-kinase (PI3K)-AKT signaling pathway. In a series of 34 patients with PTEN mutations, we described gastrointestinal lymphoid hyperplasia, extensive hyperplastic tonsils, thymus hyperplasia, autoimmune l...

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Main Authors: Heindl, M, Händel, N, Ngeow, J, Kionke, J, Wittekind, C, Kamprad, M, Rensing-Ehl, A, Ehl, S, Reifenberger, J, Loddenkemper, C, Maul, J, Hoffmeister, A, Aretz, S, Kiess, W, Eng, C, Uhlig, H
Format: Journal article
Language:English
Published: 2012

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