$Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution.$

Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution.

Reverse transcriptase (RT) from the human immunodeficiency virus type 1 has been crystallized in four closely related forms, the best of which diffract X-rays to 2.2 A resolution. The RT was crystallized as a complex with a non-nucleoside inhibitor, either nevirapine or a nevirapine analogue. Crysta...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Stammers, D, Somers, DO, Ross, C, Kirby, I, Ray, P, Wilson, J, Norman, M, Ren, J, Esnouf, R, Garman, E
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1994

Παρόμοια τεκμήρια

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2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1.
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Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation
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Έκδοση: (2009-09-01)

Isolation and characterization of monoclonal antibodies raised against the reverse transcriptase of human immunodeficiency virus type 2 and cross-reactivity with that of type 1.
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Background Activity of Reverse Transcriptases
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A reverse transcriptase ribozyme
ανά: Biswajit Samanta, κ.ά.
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Έκδοση: (1991)

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ανά: Lennerstrand, J, κ.ά.
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Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase
ανά: Stefan G. Sarafianos, κ.ά.
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Crystal structures of HIV-1 reverse transcriptase mutated at codons 100, 106 and 108 show nevirapine resistance is mediated via perturbation of interactions with Tyr181 or Tyr188
ανά: Stammers, D, κ.ά.
Έκδοση: (2002)