Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents.
Aryl azides are rapidly reduced by dithiothreitol at room temperature to the corresponding aryl amines. Glutathione and 2-mercaptoethanol react much more slowly. The relevance of this reaction to experiments involving aryl azide photoaffinity reagents is discussed. © 1978.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1978
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| _version_ | 1797068775666745344 |
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| author | Staros, J Bayley, H Standring, D Knowles, JR |
| author_facet | Staros, J Bayley, H Standring, D Knowles, JR |
| author_sort | Staros, J |
| collection | OXFORD |
| description | Aryl azides are rapidly reduced by dithiothreitol at room temperature to the corresponding aryl amines. Glutathione and 2-mercaptoethanol react much more slowly. The relevance of this reaction to experiments involving aryl azide photoaffinity reagents is discussed. © 1978. |
| first_indexed | 2024-03-06T22:14:58Z |
| format | Journal article |
| id | oxford-uuid:5313ae83-8568-40df-96b5-9779bb14851c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:14:58Z |
| publishDate | 1978 |
| record_format | dspace |
| spelling | oxford-uuid:5313ae83-8568-40df-96b5-9779bb14851c2022-03-26T16:29:24ZReduction of aryl azides by thiols: implications for the use of photoaffinity reagents.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5313ae83-8568-40df-96b5-9779bb14851cEnglishSymplectic Elements at Oxford1978Staros, JBayley, HStandring, DKnowles, JRAryl azides are rapidly reduced by dithiothreitol at room temperature to the corresponding aryl amines. Glutathione and 2-mercaptoethanol react much more slowly. The relevance of this reaction to experiments involving aryl azide photoaffinity reagents is discussed. © 1978. |
| spellingShingle | Staros, J Bayley, H Standring, D Knowles, JR Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title | Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title_full | Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title_fullStr | Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title_full_unstemmed | Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title_short | Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents. |
| title_sort | reduction of aryl azides by thiols implications for the use of photoaffinity reagents |
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