COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition.
BACKGROUND: Catechol-O-methyltransferase (COMT) metabolizes dopamine. The COMT Val(158)Met polymorphism influences its activity, and multiple neural correlates of this genotype on dopaminergic phenotypes, especially working memory, have been reported. COMT activity can also be regulated pharmacolog...
मुख्य लेखकों: | Farrell, S, Tunbridge, E, Braeutigam, S, Harrison, P |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2012
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समान संसाधन
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Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond.
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प्रकाशित: (2006) -
A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2006) -
A novel variant of catechol-O-methyltransferase increased in schizophrenia and bipolar disorder and associated with val(158)met genotype
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2005) -
Association between the Catechol O-methyltransferase (COMT) Val158met polymorphism and different dimensions of impulsivity.
द्वारा: Leandro Fernandes Malloy-Diniz, और अन्य
प्रकाशित: (2013-01-01) -
The relationship between the val158met catechol-O-methyltransferase (COMT) polymorphism and irritable bowel syndrome.
द्वारा: Pontus Karling, और अन्य
प्रकाशित: (2011-03-01)