Development of advanced three-dimensional tumour models for anti-cancer drug testing

Development of advanced three-dimensional tumour models for anti-cancer drug testing

Animal testing is still the common method to test the efficacy of new drugs, but tissue engineered in vitro models are becoming more acceptable for replacing and reducing animal testing in anti-cancer drug screening by developing <em>in vitro</em> three-dimensional (3D) tumour models for...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Wan, X
Andre forfattere:	Cui, Z
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Medical Sciences Oncology Medical Engineering Biomedical engineering Pharmacology Cell Biology (see also Plant sciences) Vascular research Life Sciences High-Throughput Screening Tumours

Lignende værker

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
af: Phipps, L
Udgivet: (2011)

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
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Udgivet: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
af: Ledaki, I
Udgivet: (2013)

Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines
af: Mallett, S, et al.
Udgivet: (2010)

Functional analysis of cancer/testis antigens in human cancer
af: Pagotto, A
Udgivet: (2013)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
af: Kesoglidou, PX
Udgivet: (2012)

Regulation of E2F-1 by methylation and NEDDylation
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Udgivet: (2012)

The role of p53 in hypoxia-induced apoptosis
af: Poole, R
Udgivet: (2010)

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
af: Colella, S, et al.
Udgivet: (2007)

Electrostatic and functional analysis of the seven-bladed WD beta-propellers
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Udgivet: (2008)

Disease model distortion in association studies
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Udgivet: (2011)

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
af: Howie, B, et al.
Udgivet: (2009)

A robust clustering algorithm for identifying problematic samples in genome-wide association studies
af: Bellenguez, C, et al.
Udgivet: (2012)

Studies on HIF hydroxylases
af: Webb, J
Udgivet: (2008)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
af: Zayer, A
Udgivet: (2012)

Tumour-stroma interaction in pancreatic cancer
af: Lunardi, S
Udgivet: (2013)

Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions
af: Lancaster, G, et al.
Udgivet: (2010)

Targeting polymer coated adenovirus to tumour-associated vasculature
af: Bachtarzi, H
Udgivet: (2010)

The influence of BRCA1's ubiquitin ligase activity on cell motility
af: Sengupta, S
Udgivet: (2014)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
af: Feldinger, K
Udgivet: (2012)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
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Udgivet: (2015)

Structure-function studies of fibronectin domains in the human endometrium
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Udgivet: (2008)

Reweighting methods in high dimensional regression
af: Fang, Z
Udgivet: (2012)

The role of Topoisomerase II in replication in mammalian cells
af: Muftic, D
Udgivet: (2011)

HR23B, a biomarker for HDAC inhibitors
af: Khan, OA
Udgivet: (2013)

Some aspects of complex statistical dependencies
af: Kartsonaki, C
Udgivet: (2014)

Synonymous codon usage influences the local protein structure observed
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Udgivet: (2010)

Markov fields and log-linear interaction models for contingency tables
af: Darroch, J, et al.
Udgivet: (1980)

Models and software for improving the profitability of pharmaceutical research
af: Qu, S
Udgivet: (2011)

Hyper Markov laws in the statistical analysis of decomposable graphical models
af: Dawid, A, et al.
Udgivet: (1993)

Graphical models for associations between variables, some of which are quantitative and some qualitative
af: Lauritzen, S, et al.
Udgivet: (1989)

Graphical models for genetic analyses
af: Lauritzen, S, et al.
Udgivet: (2003)

Some problems in the theory & application of graphical models
af: Roddam, A
Udgivet: (1999)

A coalescent dual process in a Moran model with genic selection, and the lambda coalescent limit
af: Etheridge, A, et al.
Udgivet: (2010)

How threshold behaviour affects the use of subgraphs for network comparison
af: Rito, T, et al.
Udgivet: (2010)

An approximate sampling formula under genetic hitchhiking
af: Etheridge, A, et al.
Udgivet: (2006)

A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials
af: Kikuchi, T
Udgivet: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
af: Gibson, K
Udgivet: (2011)

Course of distress in breast cancer patients, their partners, and matched control couples
af: Hinnen, C, et al.
Udgivet: (2008)

Pathways for glycoprotein degradation in mammalian cells
af: Kukushkin, N, et al.
Udgivet: (2011)