Design and synthesis of a multivalent homing device for targeting to murine CD22.

CD22 is a cell-surface glycoprotein uniquely located on mature B-cells and B-cell derived tumour cells. Current evidence suggests that binding of endogenous ligands to CD22 leads to modulation of B-cell activation by antigen. Incidentally, however, B-cell activation may derail. and lead to an undesi...

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Váldodahkkit: Sliedregt, L, van Rossenberg, S, Autar, R, Valentijn, A, van der Marel, G, van Boom, J, Piperi, C, Van Der Merwe, P, Kuiper, J, van Berkel, T, Biessen, E
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2001