The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

Individual malaria infections can carry multiple strains of Plasmodium falciparum with varying levels of relatedness. Yet, how local epidemiology affects the properties of such mixed infections remains unclear. Here, we develop an enhanced method for strain deconvolution from genome sequencing data,...

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Bibliographic Details
Main Authors:	Zhu, S, Hendry, J, Almagro-Garcia, J, Pearson, R, Amato, R, Miles, A, Weiss, D, Lucas, T, Nguyen, M, Gething, P, Kwiatkowski, D, McVean, G
Format:	Journal article
Published:	eLife Sciences Publications 2019

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