Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART.

Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART.

OBJECTIVE: To determine whether long-term HAART in chronic HIV-1 infection restores fully functional Mycobacterium tuberculosis (MTB)-specific CD4 T-cell responses. DESIGN: A cross-sectional study of HIV-1-seropositive subjects on continuous HAART for over one year with CD4 cell counts greater than...

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Bibliographic Details
Main Authors:	Sutherland, R, Yang, H, Scriba, T, Ondondo, B, Robinson, N, Conlon, C, Suttill, A, Mcshane, H, Fidler, S, McMichael, A, Dorrell, L
Format:	Journal article
Language:	English
Published:	2006

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