Novel therapeutic strategies for targeting EGFR mutated non-small cell lung cancer

<p>Background: NSCLC patients with EGFR M+ tumours have marked clinical responses to EGFR-TKIs. Most patients experience tumour regrowth, as drug resistance emerges through on-target secondary EGFR-mutations or other activating mutations that reactivate the downstream signalling. However, a...

詳細記述

書誌詳細
第一著者: Drobnitzky, N
その他の著者: Ryan, A
フォーマット: 学位論文
出版事項: 2017