Novel therapeutic strategies for targeting EGFR mutated non-small cell lung cancer

<p>Background: NSCLC patients with EGFR M+ tumours have marked clinical responses to EGFR-TKIs. Most patients experience tumour regrowth, as drug resistance emerges through on-target secondary EGFR-mutations or other activating mutations that reactivate the downstream signalling. However, a...

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Dettagli Bibliografici
Autore principale: Drobnitzky, N
Altri autori: Ryan, A
Natura: Tesi
Pubblicazione: 2017