PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.
Prostaglandin H(1) (PGH(1)) is the cyclo-oxygenase metabolite of dihomo-γ-linolenic acid (DGLA) and the precursor for the 1-series of prostaglandins which are often viewed as "anti-inflammatory". Herein we present evidence that PGH(1) is a potent activator of the pro-inflammatory PGD(2) re...
Main Authors: | Schröder, R, Xue, L, Konya, V, Martini, L, Kampitsch, N, Whistler, J, Ulven, T, Heinemann, A, Pettipher, R, Kostenis, E |
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Format: | Journal article |
Language: | English |
Published: |
2012
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