Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

N(ε)-Methylations of histone lysine residues play critical roles in cell biology by "marking" chromatin for transcriptional activation or repression. Lysine demethylases reverse N(ε)-methylation in a sequence- and methylation-selective manner. The determinants of sequence selectivity for h...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Hillringhaus, L, Yue, W, Rose, N, Ng, S, Gileadi, C, Loenarz, C, Bello, S, Bray, J, Schofield, C, Oppermann, U
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2011

অনুরূপ উপাদানগুলি

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