Crystallization of a soluble form of the rat T-cell surface glycoprotein CD4 complexed with Fab from the W3/25 monoclonal antibody.
The structure of the T-lymphocyte cell surface glycoprotein CD4 is of considerable biological and medical interest. Recombinant rat CD4 expressed in soluble form in mammalian cells and complexed with W3/25 monoclonal Fab fragments formed crystals that diffract to 3.5 A and have the orthorhombic spac...
Main Authors: | Davis, S, Brady, R, Barclay, A, Harlos, K, Dodson, G, Williams, A |
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Format: | Journal article |
Language: | English |
Published: |
1990
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