Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.

To identify susceptibility loci for visceral leishmaniasis, we undertook genome-wide association studies in two populations: 989 cases and 1,089 controls from India and 357 cases in 308 Brazilian families (1,970 individuals). The HLA-DRB1-HLA-DQA1 locus was the only region to show strong evidence of...

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Hlavní autoři:	Fakiola, M, Strange, A, Cordell, H, Miller, E, Pirinen, M, Su, Z, Mishra, A, Mehrotra, S, Monteiro, G, Band, G, Bellenguez, C, Dronov, S, Edkins, S, Freeman, C, Giannoulatou, E, Gray, E, Hunt, SE, Lacerda, H, Langford, C, Pearson, R, Pontes, N, Rai, M, Singh, S, Smith, L, Sousa, O
Médium:	Journal article
Jazyk:	English
Vydáno:	2013

Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.

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