Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.

Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.

To identify susceptibility loci for visceral leishmaniasis, we undertook genome-wide association studies in two populations: 989 cases and 1,089 controls from India and 357 cases in 308 Brazilian families (1,970 individuals). The HLA-DRB1-HLA-DQA1 locus was the only region to show strong evidence of...

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Автори: Fakiola, M, Strange, A, Cordell, H, Miller, E, Pirinen, M, Su, Z, Mishra, A, Mehrotra, S, Monteiro, G, Band, G, Bellenguez, C, Dronov, S, Edkins, S, Freeman, C, Giannoulatou, E, Gray, E, Hunt, SE, Lacerda, H, Langford, C, Pearson, R, Pontes, N, Rai, M, Singh, S, Smith, L, Sousa, O
Формат: Journal article
Мова:English
Опубліковано: 2013

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