Combined single-clade candidate HIV-1 vaccines induce T cell responses limited by multiple forms of in vivo immune interference.

We assessed in mice whether broad CD8+ T cell responses capable of efficient recognition of multiple HIV-1 clades could be induced using current single-clade vaccine constructs that were or will be used in clinical trials in Europe and Africa. We found that single-clade A, B and C vaccines applied a...

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Príomhchruthaitheoirí: Larke, N, Im, E, Wagner, R, Williamson, C, Williamson, A, Mcmichael, A, Hanke, T
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2007