Evolutionary reversals of antibiotic resistance in experimental populations of Pseudomonas aeruginosa.
Antibiotic resistance mutations are accompanied by a fitness cost, and two mechanisms allow bacteria to adapt to this cost once antibiotic use is halted. First, it is possible for resistance to revert; second, it is possible for bacteria to adapt to the cost of resistance by compensatory mutations....
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2013
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