Evolutionary reversals of antibiotic resistance in experimental populations of Pseudomonas aeruginosa.
Antibiotic resistance mutations are accompanied by a fitness cost, and two mechanisms allow bacteria to adapt to this cost once antibiotic use is halted. First, it is possible for resistance to revert; second, it is possible for bacteria to adapt to the cost of resistance by compensatory mutations....
Main Authors: | Gifford, DR, Maclean, C |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|
Similar Items
-
Population genetics of rifampicin-resistant pseudomonas aeruginosa
by: Gifford, DR
Published: (2014) -
Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade bacteria from the respiratory microbiome
by: Lindon, S, et al.
Published: (2024) -
The social evolutionary dynamics of antibiotic resistance in Pseudomonas aeruginosa infections
by: Crosse, DJM
Published: (2019) -
Environmental variation alters the fitness effects of rifampicin resistance mutations in Pseudomonas aeruginosa.
by: Gifford, D, et al.
Published: (2016) -
The genomic basis of evolutionary innovation in Pseudomonas aeruginosa
by: Toll-Riera, M, et al.
Published: (2016)