Evolutionary reversals of antibiotic resistance in experimental populations of Pseudomonas aeruginosa.

Antibiotic resistance mutations are accompanied by a fitness cost, and two mechanisms allow bacteria to adapt to this cost once antibiotic use is halted. First, it is possible for resistance to revert; second, it is possible for bacteria to adapt to the cost of resistance by compensatory mutations....

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Bibliographic Details
Main Authors: Gifford, DR, Maclean, C
Format: Journal article
Language:English
Published: 2013

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