Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore.

Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore.

Staphylococcal leukocidin pores are formed by the obligatory interaction of two distinct polypeptides, one of class F and one of class S, making them unique in the family of beta-barrel pore-forming toxins (beta-PFTs). By contrast, other beta-PFTs form homo-oligomeric pores; for example, the staphyl...

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Bibliographic Details
Main Authors:	Miles, G, Movileanu, L, Bayley, J
Format:	Journal article
Language:	English
Published:	2002

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