tidal breathing model for the multiple inert gas elimination technique
The tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas e...
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格式: | Journal article |
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1999
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author | Whiteley, J Gavaghan, D Hahn, C |
author_facet | Whiteley, J Gavaghan, D Hahn, C |
author_sort | Whiteley, J |
collection | OXFORD |
description | The tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas elimination technique (P. D. Wagner, H. A. Saltzman, and J. B. West. J. Appl. Physiol. 36: 588-599, 1974). The conservation of mass equations are solved, and it is shown that 1) retentions vary considerably over the course of a breath, 2) the retentions are dependent on alveolar volume, and 3) the retentions depend only weakly on the width of the ventilation-volume distribution. Simulated experimental data with a |
first_indexed | 2024-03-06T22:17:52Z |
format | Journal article |
id | oxford-uuid:54056875-cd02-41d4-b981-3d1dda01e8b1 |
institution | University of Oxford |
last_indexed | 2024-03-06T22:17:52Z |
publishDate | 1999 |
record_format | dspace |
spelling | oxford-uuid:54056875-cd02-41d4-b981-3d1dda01e8b12022-03-26T16:35:11Ztidal breathing model for the multiple inert gas elimination techniqueJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:54056875-cd02-41d4-b981-3d1dda01e8b1Department of Computer Science1999Whiteley, JGavaghan, DHahn, CThe tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas elimination technique (P. D. Wagner, H. A. Saltzman, and J. B. West. J. Appl. Physiol. 36: 588-599, 1974). The conservation of mass equations are solved, and it is shown that 1) retentions vary considerably over the course of a breath, 2) the retentions are dependent on alveolar volume, and 3) the retentions depend only weakly on the width of the ventilation-volume distribution. Simulated experimental data with a |
spellingShingle | Whiteley, J Gavaghan, D Hahn, C tidal breathing model for the multiple inert gas elimination technique |
title | tidal breathing model for the multiple inert gas elimination technique |
title_full | tidal breathing model for the multiple inert gas elimination technique |
title_fullStr | tidal breathing model for the multiple inert gas elimination technique |
title_full_unstemmed | tidal breathing model for the multiple inert gas elimination technique |
title_short | tidal breathing model for the multiple inert gas elimination technique |
title_sort | tidal breathing model for the multiple inert gas elimination technique |
work_keys_str_mv | AT whiteleyj tidalbreathingmodelforthemultipleinertgaseliminationtechnique AT gavaghand tidalbreathingmodelforthemultipleinertgaseliminationtechnique AT hahnc tidalbreathingmodelforthemultipleinertgaseliminationtechnique |