tidal breathing model for the multiple inert gas elimination technique

The tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas e...

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Main Authors: Whiteley, J, Gavaghan, D, Hahn, C
格式: Journal article
出版: 1999
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author Whiteley, J
Gavaghan, D
Hahn, C
author_facet Whiteley, J
Gavaghan, D
Hahn, C
author_sort Whiteley, J
collection OXFORD
description The tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas elimination technique (P. D. Wagner, H. A. Saltzman, and J. B. West. J. Appl. Physiol. 36: 588-599, 1974). The conservation of mass equations are solved, and it is shown that 1) retentions vary considerably over the course of a breath, 2) the retentions are dependent on alveolar volume, and 3) the retentions depend only weakly on the width of the ventilation-volume distribution. Simulated experimental data with a
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institution University of Oxford
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spelling oxford-uuid:54056875-cd02-41d4-b981-3d1dda01e8b12022-03-26T16:35:11Ztidal breathing model for the multiple inert gas elimination techniqueJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:54056875-cd02-41d4-b981-3d1dda01e8b1Department of Computer Science1999Whiteley, JGavaghan, DHahn, CThe tidal breathing lung model described for the sine-wave technique (D. J. Gavaghan and C. E. W. Hahn. Respir. Physiol. 106: 209-221, 1996) is generalized to continuous ventilation-perfusion and ventilation-volume distributions. This tidal breathing model is then applied to the multiple inert gas elimination technique (P. D. Wagner, H. A. Saltzman, and J. B. West. J. Appl. Physiol. 36: 588-599, 1974). The conservation of mass equations are solved, and it is shown that 1) retentions vary considerably over the course of a breath, 2) the retentions are dependent on alveolar volume, and 3) the retentions depend only weakly on the width of the ventilation-volume distribution. Simulated experimental data with a
spellingShingle Whiteley, J
Gavaghan, D
Hahn, C
tidal breathing model for the multiple inert gas elimination technique
title tidal breathing model for the multiple inert gas elimination technique
title_full tidal breathing model for the multiple inert gas elimination technique
title_fullStr tidal breathing model for the multiple inert gas elimination technique
title_full_unstemmed tidal breathing model for the multiple inert gas elimination technique
title_short tidal breathing model for the multiple inert gas elimination technique
title_sort tidal breathing model for the multiple inert gas elimination technique
work_keys_str_mv AT whiteleyj tidalbreathingmodelforthemultipleinertgaseliminationtechnique
AT gavaghand tidalbreathingmodelforthemultipleinertgaseliminationtechnique
AT hahnc tidalbreathingmodelforthemultipleinertgaseliminationtechnique