Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction.

A physical and functional interaction between the Ca(2+)-binding protein Mts1 (S100A4) and the tumor suppressor p53 protein is shown here for the first time. We demonstrate that Mts1 binds to the extreme end of the C-terminal regulatory domain of p53 by several in vitro and in vivo approaches: co-im...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Grigorian, M, Andresen, S, Tulchinsky, E, Kriajevska, M, Carlberg, C, Kruse, C, Cohn, M, Ambartsumian, N, Christensen, A, Selivanova, G, Lukanidin, E
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001