Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis.

Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis.

OBJECTIVES: To test the sensitivity to change of ultrasonographic endpoints in early phase clinical trials in subjects with active rheumatoid arthritis (RA). METHODS: A double-blind, placebo and comparator controlled, randomised, two-centre study investigated the effect on synovial thickness and va...

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Bibliographic Details
Main Authors: Seymour, M, Pétavy, F, Chiesa, F, Perry, H, Lukey, P, Binks, M, Donatien, P, Freidin, A, Eckersley, R, McClinton, C, Heath, K, Prodanovic, S, Radunovic, G, Pilipovic, N, Damjanov, N, Taylor, P
Format: Journal article
Language:English
Published: 2012

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