Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome.
X chromosome inactivation involves multiple levels of chromatin modification, established progressively and in a stepwise manner during early development. The chromosomal protein Smchd1 was recently shown to play an important role in DNA methylation of CpG islands (CGIs), a late step in the X inacti...
Κύριοι συγγραφείς: | Gendrel, A, Apedaile, A, Coker, H, Termanis, A, Zvetkova, I, Godwin, J, Tang, Y, Huntley, D, Montana, G, Taylor, S, Giannoulatou, E, Heard, E, Stancheva, I, Brockdorff, N |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2012
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Παρόμοια τεκμήρια
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Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
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Smchd1 targeting to the inactive X is dependent on the Xist-HnrnpK-PRC1 pathway
ανά: Jansz, N, κ.ά.
Έκδοση: (2018)