Epistasis in complex human traits

Epistasis in complex human traits

<p>Epistasis (gene-gene interaction) is a universal component of common complex genetic traits. The identification and characterization of epistatic interactions are crucial to a full understanding of the complex genetic mechanisms that underlie human disease. The aim of this thesis is to exam...

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Bibliografiske detaljer
Main Authors:	Bell, J, Bell, Jordana Tzenova
Andre forfattere:	Farrall, M
Format:	Thesis
Sprog:	English
Udgivet:	2006
Fag:	Genetic aspects Diabetes Research Epistasis (Genetics)

Lignende værker

Analysis of epistasis in human complex traits
af: Fonseca Ferreira, LA
Udgivet: (2023)

Mechanistic causes of sign epistasis and its applications
af: Jinqiu Zhang, et al.
Udgivet: (2024-02-01)

A strategy to apply quantitative epistasis analysis on developmental traits
af: Marta K. Labocha, et al.
Udgivet: (2017-05-01)

Estimating directional epistasis
af: Arnaud eLE ROUZIC
Udgivet: (2014-07-01)

Estimation of epistasis and genetic components of variance for different traits in cucumber (Cucumis sativus)
af: REENA KUMARI, et al.
Udgivet: (2021-09-01)

Orthogonal Decomposition of the Genetic Variance for Epistatic Traits Under Linkage Disequilibrium—Applications to the Analysis of Bateson-Dobzhansky-Müller Incompatibilities and Sign Epistasis
af: José M. Álvarez-Castro, et al.
Udgivet: (2019-03-01)

Epi-GTBN: an approach of epistasis mining based on genetic Tabu algorithm and Bayesian network
af: Yang Guo, et al.
Udgivet: (2019-08-01)

Six degrees of epistasis: Statistical network models for GWAS
af: Brett eMckinney, et al.
Udgivet: (2012-01-01)

Global epistasis emerges from a generic model of a complex trait
af: Gautam Reddy, et al.
Udgivet: (2021-03-01)

Gene buddies: linked balanced polymorphisms reinforce each other even in the absence of epistasis
af: Jacob A. Tennessen
Udgivet: (2018-06-01)

Epistasis: Searching for Interacting Genetic Variants Using Crosses
af: Ian M. Ehrenreich
Udgivet: (2017-06-01)

Analysis pipeline for the epistasis search – statistical versus biological filtering
af: Xiangqing eSun, et al.
Udgivet: (2014-04-01)

Epistasis and evolution: recent advances and an outlook for prediction
af: Milo S. Johnson, et al.
Udgivet: (2023-05-01)

Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo
af: Andrew M Taverner, et al.
Udgivet: (2019-08-01)

Cancer type‐dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types
af: Solip Park, et al.
Udgivet: (2015-07-01)

Towards a Better Basis Search through a Surrogate Model-Based Epistasis Minimization for Pseudo-Boolean Optimization
af: Yong-Hoon Kim, et al.
Udgivet: (2020-08-01)

Mutation and Epistasis in Influenza Virus Evolution
af: Daniel M. Lyons, et al.
Udgivet: (2018-08-01)

Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes
af: Sathish Periyasamy, et al.
Udgivet: (2024-01-01)

Generation mean analysis of the key earliness related traits in cowpea (Vigna unguiculata (L.) Walp)
af: Emmanuel Yaw Owusu, et al.
Udgivet: (2022-09-01)

On the mechanistic nature of epistasis in a canonical cis-regulatory element
af: Mato Lagator, et al.
Udgivet: (2017-05-01)

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding
af: Adami Christoph, et al.
Udgivet: (2003-02-01)

Foundations of generic optimization, volume 2 : applications of fuzzy control, genetic algorithms and neural networks /
af: Lowen, R.
Udgivet: (2008)

GenEpi: gene-based epistasis discovery using machine learning
af: Yu-Chuan Chang, et al.
Udgivet: (2020-02-01)

Multifactorial methods integrating haplotype and epistasis effects for genomic estimation and prediction of quantitative traits
af: Yang Da, et al.
Udgivet: (2022-10-01)

Rheumatoid arthritis identification using epistasis analysis through computational models
af: R Manavalan, et al.
Udgivet: (2020-01-01)

A Novel Mapping Strategy Utilizing Mouse Chromosome Substitution Strains Identifies Multiple Epistatic Interactions That Regulate Complex Traits
af: Anna K. Miller, et al.
Udgivet: (2020-12-01)

Genetics of grain yield and its component traits in maize (Zea mays L.)
af: Parveen Gazala1*, Erappa Gangappa1, Sampangi Ramesh1, M. S. Vedashree1 and Rajanna Raghu2
Udgivet: (2022-03-01)

Complex fitness landscape shapes variation in a hyperpolymorphic species
af: Anastasia V Stolyarova, et al.
Udgivet: (2022-05-01)

Dominance and Epistasis Interactions Revealed as Important Variants for Leaf Traits of Maize NAM Population
af: Md. M. Monir, et al.
Udgivet: (2018-06-01)

Regulatory network structure determines patterns of intermolecular epistasis
af: Mato Lagator, et al.
Udgivet: (2017-11-01)

Performance of epistasis detection methods in semi-simulated GWAS
af: Clément Chatelain, et al.
Udgivet: (2018-06-01)

Stability-mediated epistasis constrains the evolution of an influenza protein
af: Lizhi Ian Gong, et al.
Udgivet: (2013-05-01)

Deep learning captures the effect of epistasis in multifactorial diseases
af: Vladislav Perelygin, et al.
Udgivet: (2025-01-01)

Epistasis between cultural traits causes paradigm shifts in cultural evolution
af: Ignacio Pascual, et al.
Udgivet: (2020-02-01)

Global epistasis in plasmid-mediated antimicrobial resistance
af: Javier DelaFuente, et al.
Udgivet: (2024-02-01)

The impact of epistasis in the heterosis and combining ability analyses
af: José Marcelo Soriano Viana
Udgivet: (2023-04-01)

Reducing Epistasis and Pleiotropy Can Avoid the Survival of the Flattest Tragedy
af: Priyanka Mehra, et al.
Udgivet: (2024-03-01)

Allostery and Epistasis: Emergent Properties of Anisotropic Networks
af: Paul Campitelli, et al.
Udgivet: (2020-06-01)

Privacy-preserving decision tree for epistasis detection
af: Qingfeng Chen, et al.
Udgivet: (2019-02-01)

Epistasis, core-genome disharmony, and adaptation in recombining bacteria
af: Aidan J. Taylor, et al.
Udgivet: (2024-06-01)