A phase I study of the safety, tolerability and antitumor activity of escalating doses of combretastatin A4 phosphate (CA4P) given in combination with bevacizumab to subjects with advanced solid tumors

ग्रंथसूची विवरण
मुख्य लेखकों:	Nathan, P, Judson, I, Padhani, A, Harris, A, Sinha, R, Jane, B, Smythe, J, Fisher, N, Taylor, J, Collins, D, Connors, H, Gordon, R
स्वरूप:	Journal article
प्रकाशित:	2007

A phase I study of combretastatin A4 phosphate (CA4P) and bevacizumab in subjects with advanced solid tumors
द्वारा: Nathan, P, और अन्य
प्रकाशित: (2008)

Phase I trial of combretastatin A4 phosphate (CA4P) in combination with bevacizumab in patients with advanced cancer.
द्वारा: Nathan, P, और अन्य
प्रकाशित: (2012)

Vascular effects dominate solid tumor response to treatment with combretastatin A-4-phosphate
द्वारा: Jane Lunt, S, और अन्य
प्रकाशित: (2011)

The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses.
द्वारा: Prise, V, और अन्य
प्रकाशित: (2002)

Vascular effects dominate solid tumor response to treatment with combretastatin A-4-phosphate.
द्वारा: Lunt, S, और अन्य
प्रकाशित: (2011)

A Phase Ib trial of CA4P (combretastatin A-4 phosphate), carboplatin, and paclitaxel in patients with advanced cancer.
द्वारा: Rustin, G, और अन्य
प्रकाशित: (2010)

Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results.
द्वारा: Rustin, G, और अन्य
प्रकाशित: (2003)

Nitric oxide synthase inhibition enhances the tumor vascular-damaging effects of combretastatin a-4 3-o-phosphate at clinically relevant doses.
द्वारा: Tozer, G, और अन्य
प्रकाशित: (2009)

The vascular targeting agent combretastatin A-4-phosphate induces neutrophil recruitment to endothelial cells in vitro.
द्वारा: Brooks, A, और अन्य
प्रकाशित: (2003)

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts
द्वारा: Kumar, K, और अन्य
प्रकाशित: (2013)

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts.
द्वारा: Kumar, K, और अन्य
प्रकाशित: (2013)

Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer.
द्वारा: Zweifel, M, और अन्य
प्रकाशित: (2011)

Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo.
द्वारा: Galbraith, S, और अन्य
प्रकाशित: (2001)

Combretastatin A-4 phosphate (CA4P) carboplatin and paclitaxel in patients with platinum-resistant ovarian cancer: Final phase II trial results
द्वारा: Zweifel, M, और अन्य
प्रकाशित: (2009)

Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability.
द्वारा: Tozer, G, और अन्य
प्रकाशित: (2001)

A phase I trial of radioimmunotherapy with 131I-A5B7 anti-CEA antibody in combination with combretastatin-A4-phosphate in advanced gastrointestinal carcinomas.
द्वारा: Meyer, T, और अन्य
प्रकाशित: (2009)

Personalized dose escalation in anal cancer
द्वारा: Robinson, M, और अन्य
प्रकाशित: (2016)

Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4.
द्वारा: Thomson, P, और अन्य
प्रकाशित: (2006)

Dose escalation of 5ASA: does it work?
द्वारा: Travis, S
प्रकाशित: (2005)

Improved Outcomes With Dose Escalated Hypofractionated Radiotherapy for Prostate Cancer
द्वारा: Mackenzie, J, और अन्य
प्रकाशित: (2011)

Treatment planning of dose escalation for anal cancer in the PLATO trial
द्वारा: Abbott, N, और अन्य
प्रकाशित: (2017)

Bevacizumab--current status and future directions.
द्वारा: Midgley, R, और अन्य
प्रकाशित: (2005)

Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours.
द्वारा: Dean, E, और अन्य
प्रकाशित: (2012)

Is nevirapine dose-escalation appropriate in young, African, HIV-infected children?
द्वारा: Fillekes, Q, और अन्य
प्रकाशित: (2013)

Normal tissue doses during isotoxically dose escalated lung radiation therapy using MR-linacs
द्वारा: Bendall, L, और अन्य
प्रकाशित: (2018)

Influence of dose calculation algorithms on isotoxic dose-escalation of non-small cell lung cancer radiotherapy.
द्वारा: Panettieri, V, और अन्य
प्रकाशित: (2010)

Effect of Modified Vaccinia Ankara–5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial
द्वारा: Scurr, M, और अन्य
प्रकाशित: (2017)

A phase 1 dose-finding and pharmacodynamic study of rapamycin in combination with bevacizumab in patients with unresectable hepatocellular carcinoma
द्वारा: Choo, S. P., और अन्य
प्रकाशित: (2013)

Bevacizumab and type 1 idiopathic macular telangiectasia
द्वारा: Koay, C.L., और अन्य
प्रकाशित: (2011)

Biomarkers to predict the clinical efficacy of bevacizumab in cancer.
द्वारा: Jubb, A, और अन्य
प्रकाशित: (2010)

Intensity-modulated radiotherapy allows escalation of the radiation dose to the pelvic lymph nodes in patients with locally advanced prostate cancer: preliminary results of a phase I dose escalation study.
द्वारा: Guerrero Urbano, T, और अन्य
प्रकाशित: (2010)

The tolerability of single low dose primaquine in glucose-6-phosphate deficient and normal falciparum-infected Cambodians
द्वारा: Dysoley, L, और अन्य
प्रकाशित: (2019)

Clinical and dosimetric factors impacting radiation pneumonitis in isotoxically dose-escalated NSCLC
द्वारा: Vivekanandan, S, और अन्य
प्रकाशित: (2017)

Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles.
द्वारा: Mehta, S, और अन्य
प्रकाशित: (2011)

Enhanced fluorescence detection of cis-combretastatins by post-column photolysis.
द्वारा: Stratford, MR
प्रकाशित: (2008)

Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab.
द्वारा: Koukourakis, M, और अन्य
प्रकाशित: (2009)

On escalation and deterrence
द्वारा: Pool, Ithiel de Sola, 1917-1984
प्रकाशित: (2014)

Antitumor and antioxidant effects of Clinacanthus nutans Lindau in 4T1 tumor-bearing mice
द्वारा: Nik Abd Rahman, Nik Mohd Afizan, और अन्य
प्रकाशित: (2019)

Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.
द्वारा: Ruocco, MG, और अन्य
प्रकाशित: (2012)

The chemistry of antitumor antibiotics /
द्वारा: 203944 Remers, William A.
प्रकाशित: (1979)

A phase I study of the safety, tolerability and antitumor activity of escalating doses of combretastatin A4 phosphate (CA4P) given in combination with bevacizumab to subjects with advanced solid tumors

समान संसाधन

समान संसाधन